摘要
目的探讨早期干预对新生儿窒息后脑损伤发病率的影响。方法对出生时有窒息表现的新生儿在出生后6h内给予苯巴比妥钠15m g/kg,12h后给予5m g/kg,每12小时一次,维持3￣5d。结果预防用药组较对照组在新生儿窒息后的缺氧缺血性脑病、颅内出血等脑损伤的发病率有明显降低,两者相比较有显著差异(P<0.05)。结论对出生时有窒息表现的新生儿可以使用苯巴比妥钠进行早期干预。
Objective To explore the injury of neonates with asphyxiation. Methods treatment effect of sodium phenobarbital on cerebral The neonates who had asphyxiation were given with 15 mg/kg within 6 h after birth, 5 mg/kg after 12 h, twice a day, for 3-5 d. Results The incidence rate of cerebral injury, such as hypoxic-ischemic encephalopathy and intracranial hemorrhage, in the prevention group is lower than that in the control group. There was significant difference between the two groups （P〈0.05）. Conclusion It is advisable to treat the neonates with asohyxiation early with sodium nhenobarbital.
出处
《中华神经医学杂志》
CAS
CSCD
2005年第8期831-832,共2页
Chinese Journal of Neuromedicine
关键词
新生儿
缺氧缺血性脑痫
苯巴比妥钠
Neonates
Hypoxic-ischemic encephalopathy
Sodium phenobarbital
