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人工髓核假体置换术治疗腰椎间盘突出症 被引量:3

Prosthetic disc nucleus replacement for lumbar disc herniation
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摘要 目的比较人工髓核假体(PDN)置换术和传统单纯髓核摘除术治疗腰椎间盘突出症的疗效,评价人工髓核假体置换术的实用价值.方法施行人工髓核假体置换术18例,16例为单节段腰椎间盘突出症,2例为两节段腰椎间盘突出,均采用单枚PDN置入单个椎间盘间隙.对照组单纯髓核摘除术30例,22例为单节段腰椎间盘突出,8例为两节段腰椎间盘突出.观察两组病例的临床效果.结果PDN组术后临床症状均消失,运动功能明显好转.6例获得9~22个月的随访,9例获得3~9个月的随访,椎间隙高度较手术前平均增加10.5%,无髓核假体移位突出,术后疗效明显优于单纯髓核摘除术组,两者相比差异有显著性(P<0.01).结论PDN置换术既能恢复脊柱的节段稳定性,又保持脊柱节段的活动性,适当的假体设计与材料选择也能使椎间盘与椎体后柱的负荷获得再平衡,有广泛的应用前景. Objective To evaluate the clinical value of prosthetic disc nucleus (PDN-solo) replacement for lumbar disc herniation by comparing it with traditional solely discectomy, Methods 18 cases of lumbar disc herniation were treated with PDN-solo replacement, including 16 cases of single segment (9 L4-5, 7 L5 -S1 ) and 2 double segments ( L4-5 and L5 - S1 ). All were performed with single PDN-solo replacement. 30 cases of lumbar disc were treated with traditional solely discectomy as control, The ellects in the two groups were oDserveo. Results The clinical symptom in PDN-solo replacement group released totally and segment motion recovered significantly. 6 cases were follow-up for 9 - 22 months and 9 for 3 -9 months. The intervertebral height recovered 10. 5% postoperatively. No PDN-solo displacement was found. The effect was significantly better than that of traditional solely discectomy ( P 〈 0.01 ). Conclusions PDN-solo replacement can restore the stability and mobility. Suitable prosthetic design and material selection can help to rebalance the intervertebral disc and posterior column load transmission, which has wide prospective application value.
出处 《临床骨科杂志》 2005年第4期300-303,共4页 Journal of Clinical Orthopaedics
关键词 假体植人 腰椎间盘突出症 髓核 prosthesis replacement lumbar disc herniation nucleus pulposus
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