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不良妊娠结局与弓形虫感染相关性研究 被引量:3

Study on the Pertinency between Toxoplasma Gondii Infection and Poor Pregnancy Outcome in Women
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摘要 目的探讨十堰地区妇女异常妊娠与弓形虫感染的相关性。方法采用酶联免疫吸附试验检测2007年7月~2010年6月105例异常妊娠孕妇(实验组)及500例正常育龄孕妇(对照组)血清中弓形虫特异性抗体IgM、IgG,并分析两组间感染率的差异。结果异常妊娠孕妇弓形虫IgM、IgG抗体阳性率分别为13.33%和23.81%,而同时间段正常孕妇相应的IgM、IgG抗体阳性率为3.60%和9.80%。异常妊娠孕妇弓形虫IgM、IgG抗体阳性率均明显增高(P<0.001)。结论孕妇弓形虫感染是异常妊娠的重要原因之一,应重视弓形虫感染的早期筛查和诊治。 Objective To study the correlation between Toxoplasma(TOX) infection and the abnormal pregnancy in Shiyan area.Methods ELISA was used to detect the specific antibody(IgM,IgG) to TOX in sera from 105 pregnant women with the abnormal pregnancy(experimental group) and 500 normal pregnant women(control group) from July 2007 to Jun.2010.The difference of the infection rate of TOX between the two groups was statistically analyzed(χ2 test).Results Positive rates of IgM,IgG antibodies to TOX were 13.33% and 23.81% respectively in the pregnant women with abnormal pregnancy,while the relevant IgM,IgG antibodies positive rates of healthy pregnant women were 3.60% and9.80% respectively in the same period.Positive rates of IgM,IgG antibodies to TOX in the pregnant women with abnormal pregnancy were remarkable high(P<0.001).Conclusions TOX infection may be one of the important factors causing the abnormal pregnancy and more attention should be paid to the early screening,diagnosis and treatment of TOX infection.
出处 《临床输血与检验》 CAS 2011年第3期238-240,共3页 Journal of Clinical Transfusion and Laboratory Medicine
关键词 弓形虫感染 IGM抗体 IGG抗体 异常妊娠 Toxoplasma gondii infection IgM antibody IgG antibody Abnormal pregnancy
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