摘要
目的研究短暂高水平呼气末正压(positive end expiratory pressure,PEEP)肺复张对急性呼吸窘迫综合征(acute respiratory distress syndrome,ARDS)患者氧合情况及血流动力学的影响.方法 40例患者被随机分为实验组(22例)和对照组(18例),实验组采用压力控制通气+短暂高水平呼气末正压肺复张,对照组采用压力控制通气,分别对两组患者的氧合、血流动力学及预后进行比较.结果实验组氧合指标较对照组明显改善(P<0.05).结论短暂高水平呼气末正压肺复张对于改善ARDS患者的氧合是安全有效的.
Objective To study the effect of short-term high-level PEEP on oxygen metabolism and hemodynamics in patients with acute respiratory distress syndrome.Methods 40 cases with ALI/SRDS were randomly divided into study group(pressure control ventilation and short-term high-level PEEP,22 cases) and control group(pressure control ventilation only,18 cases).The changes of oxygenation,hemodynamics and prognosis of patients were compared between the two groups.Result After short-term high-level PEEP,there was a significant improving in PaO2,PaO2/FiO2(P<0.05) in the study group,but there was no significant difference in the the side effects and prognosis of patients.Conclusion Short-term high-level PEEP is effective and safe for patients with ALI/ARDS.
出处
《昆明医学院学报》
2011年第12期73-76,85,共5页
Journal of Kunming Medical College
基金
云南省自然科学基金昆明医学院第一附属医院院内资助项目(2007YN16)
云南省教育厅基金资助项目(06Y209C)
关键词
呼气末正压通气
肺保护性通气策略
急性肺损伤
急性呼吸窘迫综合征
Positive end expiratory pressure mechanical ventilation
Lung protective ventilation strategy
Acute lung injury
Acute respiratory distress syndrome
