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Lentivirus介导分泌神经营养因子-3的基因工程神经干细胞移植治疗脊髓损伤的实验研究 被引量：4

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作者 蔡培强 汤逊 林月秋 Martin Oudega Bas Blits 徐林 阳运康
机构地区 成都军区昆明总医院骨科 美国迈阿密大学医学院 荷兰阿姆斯特丹神经科学研究院 中国科学院昆明动物研究所
出处 《中华外科杂志》 CAS CSCD 北大核心 2005年第16期1091-1093,共3页 Chinese Journal of Surgery
基金 云南省自然科学基金资助项目(2002C0070M)
关键词 脊髓损伤(SCI) 神经干细胞移植治疗 神经营养因子-3 实验研究 基因工程 神经干细胞(NSC) 分泌 介导 自我更新能力
分类号 R651.2 [医药卫生—外科学]
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参考文献10

  • 1Costantini LC, Bakowska J, Breake X, et al. Gene therapy in the CNS. Gene Ther, 2000,7: 93-109.
  • 2Burns JC, Friedmann T, Driever W, et al. Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and effcient gene transfer into mammalian and nonmammalian cells. PNAS USA,1993, 90 : 8033-8037.
  • 3Zhu Y, Feuer G, Day S L,et al. Multigene lentivirus vectors based on differential splicing and translational control. Mol Ther, 2001,3 :375-382.
  • 4Iwakuma T, Cui Y, Chang L. Self-inactivating lentiviral vectors with U3 and U5 modi. cations. J Virol, 1999, 261 : 120-132.
  • 5Cui Y, Iwakuma T, Chang LJ. Contributions of viral splice sites and cis-regulatory elements to lentivirus vector function. J Virol, 1999,73: 6171-6176.
  • 6Liu Y, Himes BT, Solowska J, et al. Intraspinal delivery of neurotrophin-3 using neural stein cells genetically modified by recombinant retrovirus. Exp Neurol, 1999,158, 9-26.
  • 7Blits B, Oudega M, Boer GJ. Adeno-associated viral vector-mediated neurotrophin gene transfer in the injured adult rat spinal cord improves hind-limb function. Neuroscience, 2003, 118 : 271-281.
  • 8Lu P, Jones LL, Snyder EY, et al. Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Exp Neurol, 2003, 181 : 115-129.
  • 9Lu P, Blesch A, Tuszynski MH. Neurotrophism without neurotropism: BDNF promotes survival but not growth of lesioned corticospinal neurons. Comp Neurol, 2001,436: 456-470.
  • 10Chang MY, Son H, Lee YS, et al. Neurons and astrocytes secrete factors that cause stem cells to differentiate into neurons and astrocytes, respectively. Mol Cell Neurosci, 2003, 23: 414-426.

同被引文献21

  • 1冯东福,楼美清,卢亦成.成体神经干细胞巢[J].中华医学杂志,2005,85(32):2297-2299. 被引量：7
  • 2冯东福,卢亦成,楼美清,陈二涛,汪洋,李文生.视神经离断对神经干细胞定向诱导分化的影响[J].中华急诊医学杂志,2007,16(7):721-725. 被引量：9
  • 3Richter MW,Fletcher PA,Liu J,et al.Lamina Propria and Olfactory Bulb Ensheathing Cells Exhibit Differential Integration and Migration and Promote Differential Axon Sprouting in the Lesioned Spinal Cord[J].J Neurosci,2005,25(46):10700-10711.
  • 4Sasaki M,Karen L,Zemedkun LM,et al.Identified olfactory ensheathing cells transplanted into the transected dorsal funiculus bridge the lesion and form myelin[J].J Neurosci,2004,24(39):8485-8493.
  • 5McGee AW,Strittmatter SM.The Nogo-66 receptor:focusing myelin inhibition of axon regeneration[J].Trends Neurosci,2003,26:193-198.
  • 6Reynolds BA,Weiss A.Generation of neurons and astrocytes from isolated cells of adult mammalian central nervous system[J].Science,1992,255:1707-1709.
  • 7Nash HH,Borke RC,Anders JJ.New method of purification for establishing primary cultures of ensheathing cells from the adult olfactory bulb[J].Glia,2001,34(2):81-87.
  • 8Ying Z,Roy RR,Edgerton VR,et al.Exercise restores levels of neurotrophins and synaptic plasticity following spinal cord injury[J].Exp Neurol,2005,193(2):411-419.
  • 9Raisman G.Olfactory ensheathing cells and repair of brain and spinal cord injuries[J].Cloning Stem Cells,2004,6 (4):364-368.
  • 10Martin LV,Weston S,West AK,et al.Nerve growth factor promotes olfactory axonal elongation[J].Neuroreport,2002,13:621-625.

引证文献4

二级引证文献13

中华外科杂志
2005年 第16期

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