摘要
目的:研究伽玛刀低剂量体积分割治疗颅底大型脑膜瘤的治疗效果及并发症。方法:自1997～2009应用OUR-旋转式伽玛刀体积分割治疗颅底大型脑膜瘤共7例,其中男性4例,女性3例,年龄53～80岁。2例系术后复发,手术病检证实为脑膜瘤;5例为临床及影像诊断为脑膜瘤。肿瘤直径为42～60 mm,所有患者在伽玛刀第一次规划时设定体积分割范围及分割次数,射线单次照射病灶直径为25～30 mm,分割次数为2～3次。单次治疗周边剂量8～11 Gy,间隔时期3～9月。结果:在分割照射结束后开始随访,随访2～10年,随访7例。肿瘤生长控制率为85.6%(6/7),其中明显缩小1例,无变化5例。瘤体增大1例。临床症状改善为3例,症状无改变为3例,加重1例,症状加重系瘤体增大所致。结论:颅底大型脑膜瘤首选手术治疗,但对身体状态难以耐受手术或拒绝手术的老年患者,伽玛刀低剂量体积分割治疗是可供选择的方法。
Objective:This study investigated the efficacy of staged radiosurgical treatment for intracranial meningiomas exceeding 4 cm in diameter. Methods:Between April 1997 and May 2009,staged gamma knife radiosurgery was performed in 7patients with large benign meningiomas.2 patients had undergone surgery.The patients ages ranged between 53 and 80 years.The prescription dose at the tumour margin was 8Gyto 11 Gy.Follow-up was between 2 to 10 years. Results:Tumour control was achieved in 85.6% of our series(14.2% t...
出处
《航空航天医药》
2011年第1期5-6,共2页
Aerospace Medicine
关键词
伽玛刀
分次
脑膜瘤
Staged gamma knife radiosurgery
meningiomas
