摘要
目的了解血清胱抑素C和尿微量白蛋白在老年糖尿病患者早期肾功能损害监测中的临床意义。方法我们以2008-07-2009-08在我院就诊或住院的老年2型糖尿病患者46例为患者组,40例无糖尿病及肾病的健康老年人作为对照组,测定BUN、Scr、Ucr、UMA、Scys C和血压并用Scr、Ucr、体表面积和24 h尿量计算出CCr,将结果作统计学处理。结果患者组的BUN、Scr、UMA、Scys C和CCr均值均显著高于对照组,(P均<0.01),患者组的Scys C、CCr和UMA异常例数分别为32例(69.56%)、32例(69.56%)和30例(65.22%),高于Scr,在Scr正常者中Scys C和CCr亦有异常,分别为9例(39.13%)和9例(39.13%)。结论 Scys C和CCr对老年糖尿病患者早期肾功能损害有指导意义,但以Scys C临床适用性较好,UMA可作为糖尿病肾病早期诊断的参考指标。
Objective To estimate the early diagnostic values of the serum cystatin C and urine microalbumin in the renal function impairment of the elderly patient with type2 diabetes.Methods From 2008 October to 2009 October,blood pressure,blood urea nitrogen(BUN),serum creatinine(Scr),urine microalbumin(UMA),serum cystatin C(Scycs C) and body height and weight were determined and creatinine clearance(CCr) was calculated according to Scr,uric creatinie(Ucr),24 h uric volume and body height and weight in 48 elderly pa...
出处
《贵州医药》
CAS
2011年第1期3-5,共3页
Guizhou Medical Journal
基金
贵阳市科技局基金资助项目[(2009)筑科农合同字第3-002号]
