摘要
目的 评价健脾益肾泄浊方治疗慢性肾功能衰竭(CRF)伴营养不良患者的疗效.方法将60例CRF伴营养不良的非透析患者随机分为治疗组(30例)和对照组(30例).对照组予西医对症处理;治疗组在对照组基础上配合中药健脾益肾泄浊方(主要药物有黄芪、白术、茯苓、姜半夏、姜竹茹、熟地黄、山茱萸、生大黄、六月雪、炒槐米、丹参等,随证加减)治疗,连用6个月.两组均于治疗前后检测血清白蛋白、前白蛋白、转铁蛋白、胆固醇、血红蛋白、血尿素氮、血肌酐等指标,并对患者进行主症评分及主观综合营养评估(SGA).结果治疗组临床总有效率(90.0%,27/30)明显高于对照组(60.0%,18/30),差异有统计学意义(P<0.05).两组治疗后均可改善患者肾功能,并能升高血清白蛋白、前白蛋白、转铁蛋白、胆固醇、血红蛋白水平,降低主症评分及升高SGA评分(P＜0.05或P＜0.01);治疗组的改善程度明显好于对照组(P<0.05或P<0.01).结论健脾益肾泄浊方能改善CRF患者的营养状况,提高患者的生存质量.
Objective To evaluate the therapeutic effect of treating the malnutrition of chronic renal failure (CRF) patients by means of invigorating spleen and kidney and removing turbidity method(健脾益肾泄 浊法).Metho山Sixty cases suffered from malnutrition of CRF without dialysis were randomly divided into two groups: treatment (30 cases) and control (30 cases) groups. The control group was treated with western medicine, while the treatment group, on the basis of the control group, was additionally treated by means of traditional Chinese medicine (TCM ) prescription for invigorating spleen and kidney and removing turbidity Cmain herb medicines include: astragalus(黄蔑)，atractylodes(白术)，poria cocos(获荃)，rhizoma pinelliae (姜半夏)，caulis bambusae(姜竹茹)，rehmannia glutinosa(熟地黄), cornus officinalis(山茱芡), rhubarb (生大黄)，serissa japonica thunb(六月雪)，stir-baked floe scophorae immaturus(炒槐米)，salvia miltiorrhiza bge(丹参)，with modification according to individual symptoms and signs) for 6 months. Such indexes as serum albumin, pre-albumin, transferrin, cholesterol, hemoglobin, blood urea nitrogen (BUN) and serum creatinine were tested before and after the treatment for both groups. The scoring of main syndromes and the subjective global assessment (SGA) of nutrition were carried out for the patients. Results The clinical total effective rate of treatment group ( 90. 0%，27/30) was obviously higher than that of the control group C( 60. D 0 o , 18/30 ) , P < 0. 05 ). The treatment of both groups could improve renal functions , as well as enhance the levels of serum albumin, pre-albumin, transferrin, cholesterol and hemoglobin, reduce the score of main syndromes and raise the score of SGA (P < 0. 05 or P< 0. 0l ). The degree of improvement of the treatment group was significantly better than that of the control group (P<0. 05 or P<0. 01). Conclusion The TCM treatment of invigorating spleen and kidney and removing turbidity can improve the nutrition in patients with CRF as well as enhance their survival quality.
出处
《中国中西医结合急救杂志》
CAS
北大核心
2009年第6期348-351,共4页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
关键词
健脾益肾泄浊方
肾功能衰竭
慢性
营养不良
中医治疗
invigorating spleen and kidney and removing turbidity prescription
chronic renal failure
malnutritiona traditional Chinese medicine treatment
