摘要
目的:遴选出具有阻止磷燃、减少磷化氢生成和吸收的解毒型洗胃剂。方法:首先找到昆明小鼠灌服磷化铝混合液的最小全数致死量后,再分别用理论上对磷化铝有解毒作用的几种洗胃液分组与寻找到的昆明小鼠最小全数致死量的磷化铝混合后灌胃,观察中毒反应,比较出具有解毒型的洗胃剂。结果:食用油是最佳洗胃剂,人工排气有减毒作用。结论:口服磷化铝中毒时给予食用油洗胃和胃肠减压术,可能是提高口服磷化铝中毒抢救成功率的关键技术。
Objective:To select detoxificating lavage agents with functions of preventing phosphor burning and reducing phosphine generating.Method:After finding minimum total number of lethal quantity to a Kunming mouse with taking mixed aluminum phosphide agent orally,the Kunming mice were lavaged separately by agents mixed with several lavage agents with theoretical detoxification and aluminum phosphide in the minimum total number of lethal quantity.Effective detoxificating lavage agents were compared and selected according to observation of toxic reaction. Results:Edible oil was the best lavage agent.Manual air exhaust had effect for releasing toxic reaction.Conclusion: Treated by edible oil lavage and gastroenteric decompression in time possibly is a key technique for improving the rescue success rate of toxication caused by taking aluminum phosphide orally.
出处
《岭南急诊医学杂志》
2009年第5期379-380,共2页
Lingnan Journal of Emergency Medicine
基金
云南省教育厅资助项目(5Z0296C)
