摘要
用免疫组化(ABC法)和颈淋巴结连续切片相结合的方法,检测花生凝集素在喉癌组织中的表达特点和临床意义。发现花生凝集素在喉癌旁正常上皮中阳性表达为15%,在癌组织中阳性表达为77%;有潜在淋巴结转移组中阳性表达95%,无转移组中阳性表达57%(P<0.01)。表明喉癌组织中PNA检测,对喉癌早期癌变的诊断,特别是对潜在淋巴结转移的诊断有意义。
xpression
feature of peanut agglutinin(PNA)was researched with methids of
immunohis-tochemistry A,B,C and serial section of cervical lymph
node. Result showel 15%PNA express in nor-mal laryngeal epithelium,
77%in cancer tissue, and specially 95%express in cancer tissue with
latentcervical lymph node metastases. We think that PNA inspection
has clinical significance in eares-diagno-sising laryngeal cancer and
latent cervical lymph node metastases.
出处
《中国医科大学学报》
CAS
CSCD
1995年第3期256-257,共2页
Journal of China Medical University