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喉癌组织中花生凝集素检测及意义

Peanut Agglutinin Inspection in Laryngeal Cancer Tissue and Significancer
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摘要 用免疫组化(ABC法)和颈淋巴结连续切片相结合的方法,检测花生凝集素在喉癌组织中的表达特点和临床意义。发现花生凝集素在喉癌旁正常上皮中阳性表达为15%,在癌组织中阳性表达为77%;有潜在淋巴结转移组中阳性表达95%,无转移组中阳性表达57%(P<0.01)。表明喉癌组织中PNA检测,对喉癌早期癌变的诊断,特别是对潜在淋巴结转移的诊断有意义。 xpression feature of peanut agglutinin(PNA)was researched with methids of immunohis-tochemistry A,B,C and serial section of cervical lymph node. Result showel 15%PNA express in nor-mal laryngeal epithelium, 77%in cancer tissue, and specially 95%express in cancer tissue with latentcervical lymph node metastases. We think that PNA inspection has clinical significance in eares-diagno-sising laryngeal cancer and latent cervical lymph node metastases.
出处 《中国医科大学学报》 CAS CSCD 1995年第3期256-257,共2页 Journal of China Medical University
关键词 喉肿瘤 病理组织学 花生凝集素 laryngeal cancer peanut agglutinin
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  • 1Volker E. Dube. The structural relationship of blood group-related oligosaccharides in human carcinoma to biological function: A perspective[J] 1987,CANCER AND METASTASIS REVIEW(4):541~557
  • 2. The general rules for the gastric cancer study in surgery and pathology[J] 1981,The Japanese Journal of Surgery(2):140~145

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