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直立倾斜试验对原因不明晕厥患者诊断价值及美托洛尔疗效 被引量:11

EVALUATION OF THE UPRIGHT TILT TEST IN DIAGNOSING PATIENTS WITH UNEXPLAINED SYNCOPE AND THERAPEUTIC EFFECT OF METOPRONOL
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摘要 本研究用自制的倾斜板,对24例原因不明晕厥患者(排除心、脑和药物等因素),进行检查。21例诱发出症状,其中8例在基础状态下(占全组24例的33.3%);13例在用异丙肾上腺素静脉滴注时(占全组的54.2%)。阳性反应表现为3种类型:①心脏抑制型1例;②血管抑制型2例;③混合型18例。阳性病例给予美托洛尔50mg,每日2次,其中6例6天后行直立倾斜试验未诱发出症状。所以,直立倾斜试验对原因不明晕厥患者的诊断是一种有效的方法。美托洛尔可用来防治直立倾斜试验诱发的晕厥。 Twenty-four patients aged 20 to 45 yrs.(mean 37. 7) with unexplained syncope but with normal heart and neurologic evaluation were tested by unright tilt testwith or without isoproterenol infusion. Symptoms were elicited during tilt in 21 of the 24 patients[in 8 at baseline(33. 3%) and in 13 with isoproterenol infusion(54.2%)]. No symptoms were induced in 3 patients. Three patterns of heart rate and blood pressure response to upright tilt were obseved: 1) cardioinhibitory: 1 patient(4. 8%) with asystole, the maximal PP interval was 2. 6 S; 2) vasodepressive : 2 patients(9.5%) with minimal blood pressure of 44 mmHg; and 3) mixed:18 patients(85. 7%). 12 of the 21 positive response patients were treated with β1-blocker metopronol 50 mg bid. After 6 days 6 patients were subjected to upright tilt test again, no symptoms were elicited. Therefore, upright tilt test is a useful method which can be used not only in diagnosing unexplained syncope but also in evaluating the therapeutic effect of medicine. Metopronol can be given to prevent the syncope induced by upright tilt test.
出处 《中国循环杂志》 CSCD 1995年第4期205-207,共3页 Chinese Circulation Journal
关键词 直立倾斜试验 晕厥 美托洛尔 药物疗法 疗效 Uprighttilt test Metopronol Syncope Orthostatic hypotension
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