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冠心病后抑郁与室性心律失常的相关性研究 被引量:26

ABSTRACTS OF MAJOR ORIGINAL PAPERS Relationship of depression to ventricular tachycardia in patients with coronary artery disease
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摘要 103例冠心病人完成精神状况检查和量表评定,并接受24小时Holter监测。结果发现21例病人符合轻性或重性抑郁的诊断。阵发性室性心动过速(VT)发生率在抑郁组(28.5%)显著高于非抑郁组(3.7%)。抑郁组病人心脏变异性(HRV)明显低于非抑郁病人(65.5±38.6与94.6±29.9ms,P<0.09)。抑郁病人吸烟率及婚姻状况不良者高于非抑郁病人。应用多因素Logistic回归分析,抑郁作为危险因素对VT的发生具有显著影响。本文结果可部分解释冠心病后抑郁患者心源性死亡率增加的原因。 The purpose of this study was to examine relationship between depression and venticular tachycardia(VT)in patients with coronary artery disease(CAD).103 patients diagnosed as CAD by selective coronary angiographywere administered a standardized poychiatric interview and received 24─hour Holter ECG monitoring.It was found that21 petients (20%)met the diagncotic criteria for depression. Six of depressed patients(2.6%)and three of non-de-pressed patients(3.7%)exhibited episodes of VT during the period of 24-hour monitoring (P<0. 01).The result of multiple Logistic regression revealed a significant association between depression and occurrence of VT even after adjust-ing relevant covariates.It is concluded that the higher prevalence of VT in depressed CAD patients may help to explain their increased risk for cardiac mortality.
出处 《中国心理卫生杂志》 CSSCI CSCD 北大核心 1995年第1期1-3,共3页 Chinese Mental Health Journal
关键词 冠心病 抑郁症 室性 心动过速 相关性研究 Coronary heart disease,depression,ventricular tachycardia
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  • 1杨菊贤,徐济民.行为类型与冠心病[J]心血管病译文,1985(01).

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