摘要
为探讨静脉滴注尿激酶（ＵＫ）治疗急性心肌梗塞非创伤性的血流再通有效指标，观察溶栓治疗前后的心电图、血清酶及Ｒｉｎｄｅｘ值等变化。结果：在ＵＫ大剂量组，ｍａｘＳＴ经静脉溶栓４ｈ内下降率＞５０％，ΣＳＴ下降率＞４８％，Ｒｉｎｄｅｘ值＜１０．９。经与文献对比研究，作者认为上述指标是判定血流再通的有效指标。另外，在急性心肌梗塞早期（梗塞６ｈ内）；大剂量ＵＫ（＞９０万Ｕ／ｄ）经静脉给药后的冠状动脉再通率比中、小剂量较高。
In ofder to confirm the effect or
non-invasive coronary reperfusion index(Rindex)on acute myocardial infarction by intravenous
infusion of urokinase,the authorstudied the changes of ECG,serum enzyme and R indexbefore
and after using thrombolytic therapy. the resultwas as follows :Max ST segment was lowered by
morethan 50%,ΣST by more than 48%and R index wasless than 10.9 in the group with
intravenous injection ofa large dose of urokinase. These data were effective criteria for
assessing coronary blood fiow reperfusion. Besides. in the early stage(within 6 hrs. after onset)
of acute myocardial infarction. a higher reperfusion rate wasseen when a large dose of
intravenous urokinase( 90万U/day ) was given as compared with the use of small or medium
dose of urokinase.
出处
《中国危重病急救医学》
CAS
CSCD
1995年第2期81-84,共4页
Chinese Critical Care Medicine
关键词
心肌梗塞
急性
尿激酶
溶栓疗法
静脉
acute myocardial infarction:urokinase
intravenous throbolytic
therapy
