摘要
118例临床诊断明确的甲亢患者进行了针吸,110例作出细胞学解释。作者按涂片所见上皮细胞多形性及淋巴细胞浸润程度分四型,Ⅰ、Ⅱ及Ⅲ型与桥本病相似,作者命名为混合型甲亢,Ⅳ为单纯型甲亢。细胞形态学的改变与自身抗体滴度和病程密切相关。自身抗体(TGA、MCA)阳性滴度愈高,病程愈长,这些变化也愈明显。提示甲亢可转变为桥本病。为了避免术后永久性甲减,对甲亢传统手术指征有重新商榷的必要。所有患者应作针吸和MCA、TGA检测。如针吸为混合型,抗体测定为高滴度者不宜手术。
Biopsy of thyroid with fine needle aspiration was performed on 118 patients with Graves' disease. Cytological diagnosis was established in 110 cases. These cases were divided into four types. Type I , II and III were imilar to Hashimoto's thyroi-ditis, named mixed hyperthyroidism; and type IV was named simple hyperthyroidism. There was a significant correlation between the epithelial polymorphism, lymphoid cell infiltration duration of the disease and liters of the autoan-tibodies. It is suggested that hyperthyroidism may become Hashimoto's disease. Together with the data of other post-operative patients underwent needle aspiration we proposed that in order to prevent permanent hypothyroidism after operation, the traditional surgical indication needs to be re-evaluated. The needle aspiration and MCA, TGA assay should be taken in all patients. When a mixed type of hyperthyroidism existed and the liter of the autoanti-bodies was high, thyroidectomy should be considered with caution.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
1989年第4期212-214,共3页
Chinese Journal of Endocrinology and Metabolism
关键词
甲亢
针吸
手术指征
自身抗体
Hyperthyroidism Hashimoto's disease Needle aspiration Autoantibody
