摘要
36例上海地区增生型桥本甲状腺炎患者以同一地区的正常人为对照,作了HLA-A、-B和-DR抗原测定。患者中HLA-DR9与Bw46抗原频率均显著高于正常对照组(DR9:55.56％Vs21.97％,Bw46:25％vs 5.32％),而HLA-B15抗原频率则低于正常对照组(8.33％Vs 29.79％)。三者P值各以所测定的抗原数校正后,仅DR9的增高具统计学显著性。
Thirty-six patients of Shanghai Chinese affected with hypertrophic Hashimoto's thyroiditis were typed for HLA-A, -B and -DR antigens. High frequency of DR 9 was observed (55.56% vs 21.97%) with a P value remaining significant after being corrected for the number of antigen compared. An increased frequency of Bw 46 and a decreased frequency of B 15 were also observed, but both became statistically nonsignificant when corrected for the number of antigens studied.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
1989年第2期73-74,共2页
Chinese Journal of Endocrinology and Metabolism
