摘要
分析了24例原发性甲状旁腺机能亢进病人进行选择性颈内静脉插管取血测iPTH值与手术和病理的符合情况。发现16例正常部位的单个腺瘤和单个增生腺体病人中,病侧颈内静脉血iPTH水平较健侧明显增高,其比值≥1.9者12例;而8例纵隔部位腺瘤或多个腺体增生者,其比值皆≤1.5。共计83.3％的病人符合以上情况。再次手术的9例均符合上述标准。此检查技术对病变的甲状旁腺定位有帮助,适用于再次手术前的定位诊断。
Twenty-four patients with hyperparathyroidism comfirmed by operation and pathology, including 4 males and 20 females with the mean age of 37± 11 were studied. Adenoma was found in 16 cases and hyperplasia in 8.
1. In the patients with single adenoma or hyperplasia of parathyroid gland at the usual position (i.e. in the neck), the ratio of iPTH (abnormal / normal side) was above 1.9 (2.7±0.7 X±SD, range 1.9-4.1).
2. In those with ectopic adenoma (mediastinum, 3 cases; retrosterno-clavicular joint of right side, 1 case.) and multiple hyperplasia, the ratio was below 1.5(1,2±0.2 X±SD, range 1.0-1.5). The ratios of iPTH between the two group of patients showed significant difference(P<0.001). The consistency rate between the results of iPTH RIA and the surgical findings was 20/24(83.3%). The complete consistency was existed in 9 patients with unsuccessful surgical exploration before. Therefore this technique is very helpful in diagnosis and localization of parathyroid lesions and especially for those cases in which the parathyroid lesions were not successfully removed previously.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
1989年第1期11-13,共3页
Chinese Journal of Endocrinology and Metabolism
关键词
IHPT
IPTH
甲状旁腺
诊断
Primary hyperparathyroidism Adenoma hyperplasia Parathyroid hormone Selective venous catheterization
