摘要
本文对92例糖尿病病人,174例糖耐量低减病人及124例糖耐量正常人的ApoE表型与高脂血症关系的研究表明,糖耐量异常患者ApoE表型异常主要表现为E_(3/3)明显减少、E_(2/3)显著升高。高脂血症主要与血糖的升高呈正相关,但反映遗传基因不同的ApoE表型也与高脂血症有关。
This paper studied the relationship between apolipoprotein E isoforms and hyperlipidemia among 92 cases of diabetes mellitus, 174 cases with impaired glucose tolerance and 124 sex-age-matched controls. The results demonstrated that the patients with abnormal glucose tolerance had higher frequency of E2/3 isoforms and lower frequency of E, / , in com parison with controls. Hyperlipoproteinemia were mainly related to hyperglycemia but the Apo E isoforms which ex pressed different alleles also associated with hyperlipoproteinemia.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
1989年第2期92-94,共3页
Chinese Journal of Endocrinology and Metabolism
关键词
ApoE表型
糖耐量
高血脂病
糖尿病
Apolipoprotein E isoforms Diabetes mellitus Impaired glucose tolerance Hyperlipoproteinemia
