摘要
本文报道吸水链霉菌应城变种种内融合子ＦＲ－００８产生的新抗生素（简称ＦＲ－００８抗生素）对３种蚊虫幼虫的灭蚊活性以及蚊龄、温度、紫外线对ＦＲ－００８抗生素灭蚊活性的影响。实验证明：ＦＲ－００８抗生素对３种蚊虫幼虫均有较强的致死作用。对３龄致倦库蚊、白纹伊蚊和中华按蚊幼虫的２４ｈＬＤ＿（５０）分别为１．３３０９μｇ／ｍｌ、２．０１１３μｇ／ｍｌ和２．８３１７μｇ／ｍｌ。不同虫龄对ＦＲ－００８抗生素的敏感性不同，１龄至２龄幼虫比４龄初幼虫敏感。ＦＲ－００８抗生素，在１９℃～３１℃之间，随温度升高灭蚊效果更好。紫外线照射可显著降低ＦＲ－００８抗生素的灭蚊活性。
New Antibiotic(FR-008 ) has strong efficacy against three species of mosquitolarvae. Results showed that the LD50 was 1.3309 μml at 24 hour,0. 5021μg/ml at 48 houragainst 3rd instar Culex quinquefasciatus larva LD50 was 2. 0113μg/ml at 24 hour,0.6321μg/ml at 48 hour against 3rd instar Aedes albopictus larvael and was 2. 8317μg/ml at 24 hour against3rd instar Anopheles sinensis larvae.Ⅰ-Ⅱ instar mosquito larvae was more susceptible to FR-008 antibiotic than early Ⅳ instar. LD50was 0. 9055μg/ml at 48 hour against Ⅰ-Ⅱ instar Culexquinquefasciatus larvae,4. 7124μg/ml against early Ⅳ instar larvae. From 19℃ to 31 ℃ , the effi-cacy of FR-008 antibiotic against mosquito larvae increased with the rising of temperature.When 2.5μg/ml dilution of FR-008 antibiotic was irradiated with ultraviolet ray for 4 hours,theactivity against mosquito larvae decreased by 54%as compared with control group.
出处
《中国寄生虫病防治杂志》
CSCD
1995年第2期140-142,共3页
Chinese Journal of Parasitic Disease Control
关键词
FR-008
抗生素
致倦库蚊
白纹伊蚊
吸水链霉菌
FR-008 antibiotic Culex quinque fasciatus Aedes albopicture Anopheles sinensis larva
