摘要
采用在体与离体二种方法研究了人参茎叶、芦头总皂甙对老年、中年大鼠肝勻浆和血清脂质过氧化的影响,实验结果表明:大鼠脂质过氧化反应随增龄而增高,两种皂甙对老、中年大鼠均有明显抑制脂质过氧化作用(P<0.05和<0.00,),并在小鼠实验中得到相同的结果。
The effect of saponins isolated from the stem, leaf and rhizoma of panax ginseng on the formation of lipid peroxides in aged (30, 24 and 20 months) and middle-aged (14 months) wistar rats was studied with both in vivo and in vitro methods. The results showed: The formation of lipid perxides increased with age in rats and mice: the two saponins of ginseng stem, leaf and rhizoma can obviously inhibit the lipid peroxidation in the serum (plasma) and liver homogenate of aged and middle-aged rats (p<0.05 and<0.001). The same effect was also shown in the aged LACA mouse (18 months) experiment.
出处
《中国中药杂志》
CAS
CSCD
北大核心
1989年第5期44-46,共3页
China Journal of Chinese Materia Medica
关键词
人参
茎叶
总皂甙
脂质过氧化
free radical
lipid peroxidation
aging
Ginseng stem leaf saponin
Ginseng rhizoma saponin
