摘要
发生于内蒙古自治区某地的山羊鼻内肿瘤呈地方性流行,临床上病羊初期流出大量浆液性鼻液,随后逐渐出现呼吸困难和鼻塞音,肿瘤可侵犯周围组织引起眼球突出和头颅变形,最后死于窒息。14例山羊鼻内肿瘤的病理学研究表明,肿瘤起源于筛骨迷路粘膜的腺体(包括浆液腺和粘液腺),组织学上为腺瘤,以后可转变为腺癌,并向周围组织作浸润性生长,未见转移。2例伴透射电镜检查见瘤细胞有异型性,瘤细胞和瘤组织内未见病毒样颗粒。发生于内蒙古的山羊鼻内腺瘤和腺癌同西班牙和法国的地方性山羊鼻内肿瘤在流行病学、临床症状和病理组织学类型等方面是相似的。对其发生原因进行了讨论。
Goat intranasal tumors appeared enzootically in certain districts of Inner Mongoliaautonomous region.Clinically,the affected goats sliowed copious serous nasal discharge,then snuffle and progressively developed dyspnea,ocular protrusion and skull deforma-tions,eventually death from suffocation,The results of pathological study in 14 casesrevealed,that intranasal tumors originated from serous glands and mucous glands inethmoidal mucosa;these tumors were histologically classified as adenoma and then theymight trans form into adenocarcinoma;metastases were not found.In ultrathin sectionsviral-like particles were not observed in 2 cases.The epidemiology,clinical symptomsand pathohistological pattern of goat intranasal adenoma and adenocarcinoma in InnerMongolia were similar to those of goat enzootic intranasal tumors that had been repo-rted in Spain and France.The causes of enzootic intranasal tumors in goats werediscussed.
出处
《畜牧兽医学报》
CAS
CSCD
北大核心
1995年第5期455-461,共7页
ACTA VETERINARIA ET ZOOTECHNICA SINICA
基金
内蒙古自治区自然科学基金