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甲乙丙型肝炎病毒重叠感染及其相互关系研究 被引量:1

A STUDY ON SUPERINFECTION AND RELATIONSHIP OF HAV,HBV AND HCV.
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摘要 采用EIA法检测515例急性慢性肝炎及肝硬化患者HAV、HBV和HCV感染标志。结果表明HBV标志阳性率为93.6%。HAV、HBV和HCV单独感染者占总患者的3.3%、75.3%和1.9%;HAV和HBV重叠感染占6.2%;HBV和HCV重叠感染占6.8%。三型病毒感染关系分析表明HCV感染者抗-HBc阳性率明显低于非感染者。本文提示目前各种肝病中仍以HBV感染为主,三型肝炎病毒感染可同时存在,但HCV对HBV复制有抑制作用。 The infection markers of HAV,HBV and HCV were detected by ELA in patients with various hepatic diseases including acute viral hepatitis,chronic viral hepatitit,and cirrhosis. The results showed that infection rate of HBV was highest(93.6%);infection rate of HAV was 43.7% and infection rate of HcV was lowest(10.1%).The positive rate of Anti- HAV IgM was higher in acute viral hepatitis than that in chronic viral hepatitis.The ratio of single HBV、HAV and HCV infection was 75.3%、3.3%and 1.9%raspectively.HAV and HBV superinfection ratio was 6.2%;HBV and HCV superinfection ratio was 6.8%.80.8%(42/52)patients with anti-HCV were superinfected with HBV and/or HAV.The analysis of relationship among hepatitis A,B and C virus showed that anti-HBc positive rate in patients with anti-HCV(40.4%)was lower than that in patients without anti-HCV(61.6%),but therc was no difference in HBsAg and HBV positive rate between patients with and without anti-HCV.From this study we conclude that HBV infection is main problem in various hepatic diseases in China.HCV infection can exist with HBV and/or HAV infection,but HCV infection may suppress duplication of HBV.
出处 《现代预防医学》 CAS 1995年第4期198-200,共3页 Modern Preventive Medicine
关键词 甲型肝炎病毒 乙型肝炎病毒 HCV 重叠感染 HAV HBV HCV Superinfection
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