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胃癌发生与幽门螺杆感染关系的病理学观察

PATHOLOGIC OBSERVATION OF RALATION BETWEENTHE CARCINOMA OF STOMACH AND THE INFECTION OF HELICOBACTER PYLORI
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摘要 采用PCR技术对56例胃癌、60例慢性胃炎及12例正常胃粘膜组织作了幽门螺杆菌(HelicobacterPulori,HP)检测。结果,胃癌、胃炎及正常粘膜检出率分别为41.07%、93.33%、16.67%;提出胃癌发生与HP感染有一定关系。贲门部癌感染率极低(9.52%),胃窦部及小弯区癌组织内检出率较高(68%,37.5%),与HP易感部位在窦部及小弯处是一致的;分化型(腺样型)胃癌组织中的感染率(55.88%)比低分化型(弥漫型)者(20%)为高,2例粘液癌中未测到HP。另外,HP感染率在卫生习惯较差的人群中较高,与本文胃癌的病员来源情况一致。 By techanique of Polemerase Chain Reaction,we analvsed the infcction of 56 cases carcinoma of stomach,60 cases gastritis and 12 ccases normal gastric tissues,The results showed that:the infection rates of them were 41.07%, 93.3%and 16. 67%,The infection rates of carcinomas at the upper of stomach was very lower(9.52%),those at the middle and lower were higher(68%,37.5%).the infection rates of differencial carcinomas 55.8%,but indifferencial carcinomas were 20%.
出处 《泰山医学院学报》 1995年第3期194-195,共2页 Journal of Taishan Medical College
关键词 幽门螺杆菌 胃炎 胃癌 病理 Helicobacter Pylori carcinoma of stomach gastritis
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