摘要
文本用双抗体夹心酶联免疫吸附试验(ELISA)测定了21例无过敏史和寄生虫卵检查阴性的健康对照及29例临床确诊为特应性皮炎(AD)患者的血清总IgE水平。结果表明:(1)AD病人血清总IgE水平明显高于正常对照,经统计学处理差别非常显著(P<0.01);(2)IgE水平与临床症状有呈正相关的倾向,症状严重者IgE水平较高,反之较低,但其差别未达到统计学上有意义的程度;(3)IgE水平与家族过敏史的相关性不明显,具有家族过敏史的AD病人其血清总IgE水平较无家族史者高,但无统计学意义;IgE水平与个人过敏史的关系亦不明显;(4)並非所有AD患者的血清总IgE水平都高于对照组的几何均值,对其可能的原因进行了分析。
21 non-atopic healthy individuals served as control and29 patients with acute atopic dermatitis (AD) were studied by using double-antibody sandwich ELISA for detection of serum IgE. The geometric mean serum IgE level was found to be232 IU/ml in control group, 444 in AD patients with neither family nor personal allergic history, 548 in AD patients with family allergic history and 404 in AD patients with personal a(?)fergic history.The data above indicated that, (1) There was a significant elevation of total serum IgE in AD patients in comparison with control (P<0.01), (2) The highest serum IgE level was found in patients with family allergic history: (3) There was a tendency that the serum IgE level was roughly related with the severity of skin symptoms: (4) No correlation was found between the serum IgE level and the personal allergic history.
出处
《中国免疫学杂志》
CAS
CSCD
北大核心
1989年第4期219-221,共3页
Chinese Journal of Immunology
