摘要
对２１３例老年慢性肝病患者的乙型肝炎病毒（ＨＢＶ）和丙型肝炎病毒（ＨＣＶ）血清标志物检测发现：ＨＢＶ感染占７３．２４％、ＨＢＶｆｏＨＣＶ重叠感染占１５．４９％、ＨＣＶ感染占７．０４％、其它占４．２６％；ＨＢＶ阴性者ＨＣＶ检出率高于ＨＢＶ阳性者，肝癌和肝硬化患者较慢性肝炎患者高（Ｐ＜０．０１）；ＨＢＶ和ＨＣＶ重叠感染患者的血清白蛋白下降显著，γ－球蛋白升高明显，肝硬化并腹水和上消化道出血者多（Ｐ＜０．０１或Ｐ＜０．０５）。结果表明，老年慢性肝病患者以ＨＢＶ感染为主，其次是ＨＢＶ和ＨＣＶ重叠感染。重叠感染患者病情重、并发症多、预后差。
Hepatitis B virus (HBV) and hepatitis C virus (HCV) markers were determined in 213 elderly patients with chronic liver disease.The prevalence of HBV infection was 73.24%, HBV and HCV doubleinfection was 15.49%, HCV infection was 7.04% and others was 4.23%.The detection rate of antiHCV in patients with HBV marker postitive was higher than in patients with HBV negative and higher in patients with hepatoma and liver cirrhosis than in patients with chronic hepatitis (P<0.01).In the HBV and HCV double-infection patients, the serum albumin level was reduced and gamma globulin elevated. In cirrhosis patients with ascites and upper gastrointestinal bleeding, there were more double-infection. These findings indicated that in elderly patients, the major infection was HBV, followed by HBV and HCV double-infection. For double-infection,the condition was serious and the prognosis was bad.
出处
《实用老年医学》
CAS
1995年第3期110-112,共3页
Practical Geriatrics
