摘要
高速DNA序列分析是人类基因组研究的关键技术.文章对高速DNA序列分析方法如阵列毛细管电泳、超薄层凝胶板电泳、质谱、杂交法、原子探针法、流动单分子荧光检测法等新进展进行了评论.
High-speed DNA sequence analysisis a central technology in biological andbiomedical research.The progress in high-speed DNA sequencing such as the ultrathinslab gel electrophoresis,capillary array elec-trophoresis,mass spectrometry,sequencingby hybridization,atomic prope microscopy(scanning tunneling or atomic force mi-croscopy),and single molecule fluorescencedetection in fIowing samplf streams are re-viewed.
出处
《生物化学与生物物理进展》
SCIE
CAS
CSCD
北大核心
1995年第3期223-227,共5页
Progress In Biochemistry and Biophysics
基金
国家自然科学基金及国家教委博士点基金
关键词
DNA
序列分析
电泳
DNA sequencing,DNA elec-trophoresis,capillary array electrophoresis,ultrathin slab gel electrohporesis