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慢性肾衰脂质过氧化异常和微量元素相关的研究 被引量:1

Lipid Peroxidation Abnormalities and Their Correlation with Trace Elements in Chronic Renal Failure Patients
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摘要 对30例慢性肾衰(CRF)患者作血清及红细胞中超氧歧化酶(SOD)、血清丙二醛(MDA)及多种微量元素的测定,结果显示:CRF患者血清MDA水平显著升高,血透和非透析组血清锌的下降与红细胞SOD活性下降正相关,腹透组血清铝的升高与红细胞SOD活性下降负相关,血透患者透析后SOD活性较透析前明显升高。 We determined the plasma superoxide dismutase(SOD),erythrocyte SOD,plasma levels of malonyl-dialdehyde(MDA)and plasma Zinc(Zn),copper(Cu),selenium(Se),aluminium(Al)and cadium(Cd)in 30 chronic renal failure(CRF)patients. The results showed: plasma Zn,Se,SOD activity and RBC-SOD activity were significantly low in CRF,while plasma Al and MDA were elevated.There was a positive correlation between the plasma Zn levels and RBC-SOD activity in the hemodialyzed and nondialyzed uremic patients. There was also a negative correlation between plasma Al levels and RBC-SOD activity which tends to improve after a single hemodialysis.
出处 《上海第二医科大学学报》 CSCD 1995年第2期101-104,共4页 Acta Universitatis Medicinalis Secondae Shanghai
关键词 慢性 肾功能衰竭 超氧化物歧化酶 微量元素 trace elements superoxide dismutase malonyl-dialdehyde
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  • 1戴龙君,李宏英,丁鼎武.自由基与缺血性肾脏损伤[J]国外医学泌尿系统分册,1986(03).

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