摘要
肌苷制剂的高效液相色谱法测定梁竹，于燕莉（济南军区总医院药剂科济南２５００３１）１前言肌苷为辅酶类药物。部颁标准￣［１］采用紫外分光光度法测定其制剂含量。因ｐＨ的限制，肌苷注射派均以苯甲酸钠为助溶剂，故标准又采用纸色谱－紫外法，以排除苯甲酸钠的干扰。...
high performance liquid chromatographic method was established for the determination of inosine intablet,capsule and injection. Sodium benzoate can also be determined.The mobile phase consists of a mixture ofmethanol-water,30:70(V/V).Metronidazole is used as the internal standard.The analytical column is Nucleosil C_(18),7μ.The average recoveries for inosine and sodium benzoate were 99.37±0.62%and 98.83±0.44%.
出处
《色谱》
CAS
CSCD
北大核心
1995年第6期485-486,共2页
Chinese Journal of Chromatography
关键词
肌苷制剂
高效液相色谱
igh performance liquid chromatography,inosine,sodium benzoate
