摘要
择期外科手术患者，分为两组：１．静吸复合全麻组（ｎ＝１１），平均年龄６０．７２岁，术前并发冠心病高血压；２．颈丛麻醉组（ｎ＝１１），平均年龄４１．１８岁，术前无高血压，颈丛阻滞后出现血压剧升及心率增快者。两组病人麻醉期间当ＳＢＰ高于２１．３０ｋＰａ及ＤＢＰ高于１２．００ｋＰａ时，即静注乌拉地尔２５ｍｇ，给药后每５ｍｉｎ测定ＳＢＰ、ＤＢＰ、ＨＲ并计算ＲＰＰ。结果：全麻组高血压患者静注乌拉地尔后５～１０ｍｉｎ，ＳＢＰ、ＤＢＰ、ＲＰＰ均缓和下降至正常范围（Ｐ＜０．００１），而ＨＲ无明显变化（Ｐ＞０．０５）。颈丛组静注乌拉地尔后５～１０ｍｉｎ，ＳＢＰ、ＤＢＰ均可降至正常范围（Ｐ＜０．００１），而ＨＲ、ＲＰＰ虽亦明显下降（Ｐ≤０．００１），但未降至正常范围。本文提示，乌拉地不适用于并发冠心病的高血压病人在围术期中的应用，而对颈丛阻滞后的心血管反应，虽有一定的作用，但并不满意。
he hypotensive effect of urapidil was studied in 22patients,who were anesthetized either by intravenous-in-halationaI technic(group G,n=11)or cervical plexus block(group C,n=11).Urapidil,25 mg iv was given whenSBP was greater than 21 3 kPa and DBP 12.0 kPa in both groups. Results show that in group G,the SBP DBP andRPP returned to normal affter i.v. urapidil( P<0. 001)but, the HR was not changed and in group C,the SBPDBP returned to normal(P<0. 001)while the increase of HR and RPP didn’t.It is suggested that urapidil is effec-tive in the management of periOperative hypertension.
出处
《临床麻醉学杂志》
CAS
CSCD
北大核心
1995年第3期147-148,共2页
Journal of Clinical Anesthesiology
