摘要
用放免法测定14例前列腺癌,60例前列腺增生,60例慢性前列腺炎以及40例非前列腺疾病患者的血清PSA值;并随访观察8例前列腺癌患者接受内分泌治疗后PSA值变化。表明前列腺癌PSA阳性率明显高于其它疾病组(P<0.01),其敏感性为92.9％,特异性不高,为74.4％,作为前列腺癌的筛选指标有一定局限性。但对癌分期,疗效监测有较大价值;其数值升高或下降与临床主观和客观反应呈正相关关系。
Serum prostate specific antigen. (PSA) was measured with radio - immunologic method in 14 pa-tients with prostatic carcinoma, 60 with BPH, 60 with chronic prostatitis and 40 with non - prostatic diseases. The change of PSA has also been observed in 8 cases with prostatic carcinoma who were treated by endocrine therapy. A significant difference in the positive rate of PSA was found between prostatic carcinoma and all the others(P<0. 01). The sensitivity of PSA in detecting prostatic carcinoma was 92. 9% ,Whereas its specificity was 74. 4%. Although PSA is limited as a marker in screening prostatic carcinoma, PSA minght be of value for staging. Prognosing and monitoring the disea.se. The clinical symp-toms and objective sign were significantly correlated with the level of PSA in the serum.
出处
《兰州医学院学报》
1995年第2期80-81,共2页
Journal of Lanzhou Medical College
