摘要
目的:探讨HBV-DNA阳性患者血清甘胆酸(CG)水平测定的临床意义。方法:以PCR法测定的196例HBV-DNA阳性患者作为感染组,120例健康体检者作为对照组,检测两组空腹血清CG和ALT、T-Bil的水平(CG用RIA,ALT及T-Bil用生化法)。结果:血清CG、ALT水平与对照组比较均显著升高(P<0.01),T-Bil无显著性差异(P>0.05),CG的阳性检出率高达76.0%(149/196)。结论:血清CG测定对HBV-DNA阳性患者具有重要的临床意义,优于常规肝功能检查。
Objective To investigate the clinical meanings of determination of serum CG levels in HBV - DNA positive patients. Methods Serum CG （with RIA）, ALT and total bilirubin （T - Bil） levels （with biochemistry method） were determined in 196 HBV -DNA positive patients （detected with PCR） and 120 controls. Results Serum levels of CG, ALT were significantly higher in the HBV- DNA positive patients than those in the controls （P 〈0.01 ）, however, serum T- Bil levels in the two groups were about the same （P 〉0.05）. In 76.0% （149/196） of the patients the serum CG levels were significantly higher than normal. Conclusion CG level is a sensitive marker for detection of early impairment of liver function.
出处
《放射免疫学杂志》
CAS
2005年第4期262-264,共3页
Journal of Radioimmanology
