摘要
Objective： To analyze the efficacy of six antibiotic methods for treating non- gonococcal urethritis /cervicitis and the factors influencing efficacy. Methods： Retrospective analysis of 878 nongonococcal urethritis / cervicitis cases which received regular treatment and follow-up in our institute from 1st Jan. 2001 to 31st Aug. 2003. Results： The mean cure rate of six methods for Chlamydia trachamatis （Ct） was 57.116%. There were distinct differences among these methods for Ct treatment.The mean cure rate of six methods for Ureaplasma urealyticum （Uu） was 69.556% and there was no difference among these methods for Uu treatment. Coinfection with Ct and Uu dramatically reduced the elimination rate of these two pathogens. Conclusion： The effectiveness of treatment of these antibodies for non-gonococcal urethritis / cervicitis is not currently satisfactory. Importantly, there were many antibiotic-resistant Ct and Uu strains. The factors influencing antibiotic efficacy and mechanisms need further study.
目的分析六种抗生素使用方案治疗非淋菌性尿道(宫颈)炎的效果及影响因素。方法对2001年1月1日至今我所性病门诊的878份有随访的非淋菌性尿道(宫颈)炎的病历进行回顾性分析。结果六种方案对沙眼衣原体的平均治愈率为57.116%,且不同方案的治愈率有显著性差异;六种方案对解脲支原体的平均治愈率为69.556%,不同方案的治愈率无显著性差异;衣原体和支原体的混合感染显著降低了各自的清除率。结论当前非淋菌性尿道(宫颈)炎的治疗效果并不乐观,耐药株的不断出现值得广泛关注;治疗方案疗效的影响因素及机理有待深入研究。
