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混合型胶质细胞瘤的手术处理

SRGICAL MANAGEMENT OF MIXED GLIOMAS
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摘要 本文对83例混合型胶质细胞瘤(MG)进行分析,44例为Ⅰ或Ⅱ级;39例为Ⅲ或Ⅳ级。47%瘤组织由相等量的少枝胶质细胞与星形细胞两种成分构成;38%其成分以少枝胶质细胞为主;余15%瘤组织主要成分为星形细胞。均行手术处理并辅以放疗。长期随访表明平均生存期和5、10及15年生存率分别为7.5年、51%、31%和18%。作者尚观察到具有少枝胶质细胞成分为主的肿瘤易侵入多个脑叶、基底节或丘脑区,且这类病人预后不良。 Among the 83 patients with mixed gliomas studied, 44 were classified as grade l or 2,and39 as grade 3 or 4. Two glial components(oligodendrocytes and astrocytes)were found in equal amountin 47%, predominant oligodendrocytes in 38%, and astrocytes in l5%, All the patients underwent surgi-cal treatment or surgery plus postoperative radiation therapy. Follow-up data showed that their mediansurvival time was 7.5 years, and the 5-,1O-, and l5- year survival rates were 5l%, 3l%and l8% re-spectively. The authors found that tumors with predominant oligodendroglial cells could easily invade intomultiple lobes, basal ganglia or thalamus, and their prognosis was poorer than that of the others。
出处 《解放军医学杂志》 CAS CSCD 北大核心 1995年第2期86-87,共2页 Medical Journal of Chinese People's Liberation Army
基金 国家自然科学研究基金
关键词 脑肿瘤 胶质细胞瘤 手术 Brain tumor Mixed glioma Surgical management
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