摘要
目的:比较鞘内注射芬太尼和静注恩丹西酮对剖宫产术中恶心、呕吐的抑制作用.方法:将硬膜外麻醉下行剖宫产者45例(ASA分级Ⅰ～Ⅱ级)随机均分为对照组、芬太尼组和恩丹西酮组,比较三组产妇术中出现恶心、呕吐的情况,并对娩出婴儿进行Apgar评分.结果:对照组、芬太尼组、恩丹西酮组的恶心发生率分别为5例(33.3%)、1例(6.7%)、2例(13.3%),三组统计比较无明显差异;对照组的呕吐或干呕的发生率4例(26.7%)则高于芬太尼组0例(0%)和恩丹西酮组0例(0%,P<0.05),而芬太尼组和恩丹西酮组呕吐或干呕的发生率无显著差异.三组娩出婴儿的Apgar评分无显著差异(P>0.05).结论:鞘内注射芬太尼可减少硬膜外麻醉下产妇术中呕吐的发生率,其效果与静注恩丹西酮类似.
Objective：To compare the inhibiting effect of intrathecal（IT） fentanyl and intravenous （Ⅳ） ondansetron on intraoperative nausea and vomiting during cesarean delivery under epidural anesthesia. Methods：45 healthy parturients （ASA grade Ⅰ to Ⅱ ） were randomly assigned in equal numbers into controlled, fentanyl and ondansetron groups （ n=15each, seperatly, parturients in the controlled group treated with IT saline 3ml,parturients in the fentanyl group treated with IT fentanyl 15μg， 3ml^-1 ,parturients in the ondansetron group treated with IV ondansetron 4rag）. The incidence of nausea and vomiting during cesarean delivery under epidural anesthesia among the 3 groups were compared and the neonate＇ Apgar scorces were assessed after delivery. Results：Introperative nausea and vomiting/retching were reduced in the fentanyl group and ondansetron group as compared with the controlled group（6.7% vs 13.3% vs 33.3% ,P〉0.05 ;0% vs 0% vs 26.7% ,P〈0.05 ）. The neonate＇Apgar scorces were not significantly different among the 3 groups（ P〉0.05）. Conclusion：IT fentanyl and IV ondansetron can decrease introperative vomiting during cesarean delivery performed under epidural anesthesia. The effect of both are not different.
出处
《军医进修学院学报》
CAS
北大核心
2005年第4期269-270,共2页
Academic Journal of Pla Postgraduate Medical School
关键词
麻醉
硬膜外
麻醉
静脉内
芬太尼
恩丹西酮(玉枢丹)
剖宫产术
分娩并发症
anesthesia epidural
anesthesia, intravenous, fentanyl
ondansetron （ Yushu dan）
cesarean section
labor complications
