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贺普丁联合α-干扰素治疗慢性乙型肝炎的疗效观察

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摘要 观察并总结了贺普丁联合α-干扰素治疗慢性乙型肝炎30例。结果表明联合治疗组治疗12个月,HBVDNA阴转率高达86.67%,与单独贺普丁组63.3%相比,差异有显著性(P<0.05),与单独干扰素46.67%相比,差异亦有显著性(P<0.01)。更加可喜的是联合治疗组治疗12个月时,HBeAg/Anti-HBe血清转换率达66.67%,而对照单独贺普丁组为43.33%,单独干扰素组为40.00%,经统计学分析均P<0.05,差异有显著性。联合抗病毒治疗,YMDD的变异率明显较单独贺普丁治疗组低(P<0.05),而单独干扰素组治疗期间没有发现YMDD变异。
出处 《中国微生态学杂志》 CAS CSCD 2005年第4期295-295,共1页 Chinese Journal of Microecology
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