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再次肝移植八例报告

A report of 8 cases of liver retransplantation
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摘要 目的分析影响再次肝移植手术效果的因素,总结经验和教训。方法回顾性分析8例再次肝移植患者的临床资料、手术方法及术后治疗。结果例1因术后全身严重感染、多器官功能衰竭死亡。例4因手术难度大,出血量较多,术后因多脏器衰竭死亡。例7因术后早期出现颅内出血并腹腔内感染死亡。其余5例患者术后肝功能恢复,均已出院。结论患者再次肝移植术前一般情况较差、合并严重并发症,加之手术难度加大、手术时间延长以及术中大量出血等因素,对预后均有不良影响。 Objective To summarize the experience of liver retransplantation, as well as thefactors in fluencing the surgical effects. Methods The clinical data of 8 patients who received liver retransplantation in our center were analyzed retrospectively. Results Among 8 cases, complications of biliary tract occurred in 5 cases, chronic rejections in 2 cases, embolism in hepatic artery in one case. Infections occurred in 7 cases before engraftment. Case l had developed renal function failure before the surgery, and he died of severe infections and multi-organ failure after transplantation. Case 4 had massive hemorrhage during the operation and also died of multi-organ failure after transplantation. Case 7 developed intracanial hemorrhage and abdominal infection and died early after transplantation. Other 5 cases has recovered and left hospital. Conclusions Liver retransplantation is the only measure that can be taken to save the lives of patients whose liver allograft fails to function. Its very important that the indications and time of retransplantation should be carefully selected. Factors that may lead to harmful effects on liver retransplantation include bad preoperative condition of the recipient, tough and long operation, massive hemorrhage during the operation, and severe complications after the surgery.
出处 《中华器官移植杂志》 CAS CSCD 北大核心 2005年第8期452-454,共3页 Chinese Journal of Organ Transplantation
关键词 再次肝移植 手术方法 术后治疗 多器官功能衰竭 术后感染 Liver transplantation Retrospective studies Treatment outcome
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参考文献5

  • 1Yao FY, Saab S, Bass NM,et al. Prediction of survival after liver retransplantation for late graft failure based on preoperative prognostic scores. Hepatology, 2004, 39: 230-238.
  • 2Yoo HY, Maheshwari A, Thuluvath PJ. Retransplantation of liver: primary graft nonfunction and hepatitis C virus are associated with worse outcome. Liver Transpl, 2003, 9: 897-904.
  • 3Ogura Y, Kaihara S, Haga H, et al. Outcomes for pediatric liver retransplantation from living donors. Transplantation,2003, 76:943-948.
  • 4Dudek K, Nyckowski P, Zieniewicz K, et al. Liver retransplantation: indications and results. Transplant Proc, 2002, 34: 638-639.
  • 5Meneu-Diaz JC, Vicente E, Moreno-Gonzalez E, et al. Indications for liver retransplantation: 1087 orthotopic liver transplantations between 1986 and 1997. Transplant Proc, 2002, 34:306.

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