摘要
目的:总结分析腹部外科手术后病人发生呼吸抑制的高危因素。方法:回顾性分析2002年10月至2003年7月我院在气管插管全麻下进行的腹部外科手术患者235例的临床资料。收集病人的性别、年龄、体重指数、术前肝肾功能、有无基础肺部疾病、有无阻塞性睡眠呼吸暂停征(OSAS)、手术方式、麻醉时间及输血量等指标。根据术后是否发生呼吸抑制分为两组,采用率的χ2检验和均数t检验,分析两组病人之间指标的差别。结果:有统计学差别的指标:年龄大(P<0.01)、体重指数高(P<0.01)、术前有肝肾功能不全(P<0.01)、术前有肺部基础疾病(P<0.01)、合并阻塞型睡眠呼吸暂停征(P<0.01)以及上腹部手术(P<0.05),而与麻醉时间和术中输血量无明显关系(P>0.05)。结论:年龄大、体重指数高、术前有肝肾功能不全、上腹部手术、术前有肺部基础疾病以及合并阻塞型睡眠呼吸暂停综合征的腹部外科术后病人容易发生呼吸抑制。针对有上述因素的高危人群应加强术后监护,预先采取针对性的医疗护理措施。
Objective： To investigate retrospectively the high risk factors causing respiratory depression in patients after abdomined operations. Methods： From October 2002 to July 2003, all data of the 235 patients who underwent .abdominal surgery with intratracheal anesthes were studied retrospectively, including gender, age, BMI, liver and renal functions, underlying pulmonary disease, obstructive sleep apnea syndrome, location of surgery, anesthesia time and transfusion unit. The patients were divided into two groups according to the presence of postoperative respiratory depression. Statistical analysis consisted of both a T-test and Kaplan - Meier estimation. Results： The high risk factors included age （ P 〈 0.01 ）, BMI （ P 〈 0.01 ）, liver and renal function （ P 〈 0.01 ）, location of surgery （ P 〈 0.05 ）, underlying pulmonary disease （ P 〈 0.01 ） and obstructive sleep apnea syndrome （P〈0.01）. Conclusion： The age, obosity, liver and renal dysfunction, upper abdominal surgery, having underlying pulmonary diseases and obstructive sleep apnea syndrome were liable to develop postoperative respiratory depression.
出处
《华西医学》
CAS
2005年第3期443-444,共2页
West China Medical Journal
