摘要
目的观察心房颤动(房颤)病人血浆D-二聚体(D-dimer)水平的变化,并探讨其意义。方法应用免疫比浊法测定63例房颤病人(其中风心病22例,冠心病41例)和20例正常人血浆D-二聚体。结果房颤病人与正常人相比,房颤病人血浆D-dimer浓度为(252.2～456.6)mg/L,显著高于正常人(102.6～389.8)mg/L(P<0.01);风心病病人D-dimer浓度(262.0～446.5)mg/L与冠心病病人D-dimer浓度(252.2～456.6)mg/L比较,无统计学意义。结论房颤病人血浆D-dimer水平升高,与其高发血栓栓塞并发症有关,通过检测血中D-二聚体水平的改变,有助于了解房颤发生血栓栓塞的危险程度。
Objective To study the clinical significance of D- dimer in atrial fibrillation （AF）, Methods The levels of D- dimer in 63 patients （pts） with AF （22 pts with rheumatic heart disease and 41 pts with coronary heart disease） and in 20 normal controls. Results The level of D- dimer in pts with AF （252.2-456.6）mg/L is higher significantly than that in controls（ 102.6-389.8）mg/L,（P＜0. 01）. There is no difference（P＞0.05） between pts with rheumatic heart disease（262.0 mg/L-446.5 mg/L） and pts with coronary heart diseases （252.2 mg/L-456.6 mg/L,）. Conclusions The increase of D - dimer in pts with AF may be related to the high risk of thrombosis. Testing the level of D - dimer for pts with AF may help to find out the dangerous degree of thrombosis.
出处
《中西医结合心脑血管病杂志》
2005年第8期664-665,共2页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
基金
广东省清远市科学技术局立项基金课题[No.清科字(2001)29号]
关键词
心房颤动
D-二聚体
血栓
atrial fibrillation（AF）
D- dimer
thrombosis
