2Schilling C H, Letscher D, Palsson B O Theory for the systemic defination of metabolic pathways and their use in interpreting metabolic fuhction from a pathway-oriented perspecteve[J]. J Theor Biol, 2000, 203(2):229- 248.
3Schilling C H, Palsson B O Assessment of the metabolic capabilities of H influenzae Rd through a genomic scale pathway analysis[J]. J Theor Biol, 2000, 203:249 - 283.
4Schuster S, Bandekar T, Fell D A Detection of elementary flux modes in biochemical networks: a promising tool for pathway analysis and metabolic engineering[J]. Trend Biotechol, 1999, 17(2) :53 - 60.
5Schuster R, Sehuster S. Refined algorithm and computer program for calculating all nonnegative fluxes admissible in steady states of biochemical reaction systems with or without some flux rates fixed[J]. Comp Appl Biosci, 1993, 9:79- 85.
6Edwards J S, Ibarra R U, Palsson B O. In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data [J]. Nat Biotechnol, 2001, 19: 125~ 130.
7Heinrich R, Schuster S. The regulation of cellular systems[M]. New York:Chapman & Hall, 1996.
8Mavrovouniotis M L, Stephanopoulos G. Computer aided synthesis of biochemical pathways [J]. Biotechnol Bioeng,1990, 36:1119~1132.
9Varma A, Palsson B O. Metabolic capabilities of Escherichia coli:I. Synthesis of biosynthetic precursors and cofactors [J]. J Theor Biol, 1993, 165:477~502.
10Bonarium H .P J, Schmid G, Tramper J. Flux analysis of underdetermined metabolic networks:the quest for the missing constraints [J]. Trends Biotechnol, 1997, 15 : 308~ 314.