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8种中药水煎剂与免煎颗粒剂对临床菌株的体外抑菌作用研究 被引量:11

The in Vitro Antibiotical Effect of the Single Chinese Herbal Decoction and the Single Herbal Concentrate-granules against Clinical Bacterial Strains
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摘要 目的比较8种中药的水煎剂与免煎颗粒剂对56株临床分离金黄色葡萄球菌的体外抑菌效果。方法采用M-H琼脂稀释法检测8种中药水煎剂与免煎剂对MSSA,MRSA的抑菌作用,测定最低抑菌浓度MIC50和MIC90,并加以比较。结果8种中药抑菌强度不同,五倍子抑菌效果最好;除五倍子、连翘外,其余中药水煎剂抑菌效果比相应的免煎颗粒剂好。结论中药水煎剂与免煎颗粒剂抑菌效果的差异,可能与制备工艺及原药材品质有关。 Objective:To compare the in vitro antibiotical effect of Chinese herbal decoction and single herbal concentrategranules for 8 traditional Chinese medicines against clinical Staphylococcus aureus Rosenbach. Methods: The antibiotical effect of single herbal decoction and single herbal concentrate-granules for 8 traditional Chinese medicines against MSSA and MRSA was detected and compared by M--H agar dilution method, with MICS0 and MIC90 determined. Results:Eight traditional Chinese medicines showed different antibacterial activities , with Galla Chinensis being the most potent. The antibiotical effect of single herbal decoction was better than that of single herhal concentrate- granules for Chinese traditional medicines except Galla Chinensis and Fructus Forsythiae. Conclusion: Difference of antibiotical effect between single herbal decoction and single herbal concentrate--granules maybe related to preparation technologies and qualities of raw medicinal materias.
出处 《时珍国医国药》 CAS CSCD 北大核心 2005年第8期734-736,共3页 Lishizhen Medicine and Materia Medica Research
关键词 中药水煎荆 免煎颗粒剂 抑菌作用 最低抑菌浓度 Traditional Chinese Single herbal decoction Single herbal concentrate--granules Antibiotical effect MIC
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