摘要
目的观察更昔洛韦(Ganciclovir,GCV)治疗小儿麻疹的临床疗效及安全性。方法将麻疹患儿61例随机分为治疗组33例,应用GCV5～10mg/kg·d,静脉滴注5天;对照组28例用病毒唑治疗,前瞻性地比较两组的临床疗效。结果GCV治疗组在住院、退热、咳嗽消失等的时间均比病毒唑对照组明显缩短(P<0.05),并发肺炎比率明显减少(P<0.05),而皮疹的消退时间则无显著性差异(P>0.05)。结论GCV对小儿麻疹有明显疗效。
Objective To explore the clinical curative effect and safety of Ganciclovir for child measles.Methods There were 61 cases of measles who were randomly divided into two groups. There were 33 cases who were admitted into group A, which were given 5-10 mg/kg Ganciclovir everyday through intervenous drop infusion for 5 days. And there were 28 cases who were admitted into group B, which were given Ribavirin for 5-10 mg/kg through intervenous drop infusion for 5 days. The clinical effect of the two strategies were compared prospectively. Results The duration of group A about hospitalization, pyretoiysis, and disappearance of cough were shorter than that of group B （P〈0.05）. So was the ratio of complicating pneumonia （P〈0.05）. But there was no significant difference about the regression time of rash between the two groups（P〉0.05）. Conclusions Ganciciovir is one of obviously effective drug for child measles.
出处
《海南医学》
CAS
2005年第9期57-58,共2页
Hainan Medical Journal
关键词
麻疹
更昔洛韦
小儿
Measles, Ganciclovir, Child.
