摘要
目的:探讨全肺照射联合PF方案对鼻咽癌肺转移的疗效。方法:回顾分析81例鼻咽癌肺转移的随访资料,根据治疗方法不同分为小剂量全肺照射联合PF方案组和单纯化疗组,应用χ2检验分析肿瘤的缓解率和患者生存率。结果:放疗联合化疗组于病灶消失、缩小方面优于单纯化疗组,未控/进展情况少于单纯化疗组,两者差异有显著意义(P<0.05～0.01),而疗后病情稳定两组差异无显著性(P>0.05);放疗联合化疗组与单纯化疗组的12个月生存率差异无显著意义(P>0.05),而放疗联合化疗组18个月、24个月、≥36个月生存率明显高于单纯化疗组(P<0.05～0.01)。结论:小剂量全肺照射联合PF方案对鼻咽癌肺转移的治疗是目前较为理想的治疗方案。
Objective To explore the therapeutic efficacy of whole lung irradiation combined with PF regimen in the treatment of lung metastases from nasopharyngeal carcinoma (NPC). Methods Follow-up data of 81 cases with lung metastases from NPC were analyzed retrospectively. The patients were divided into two groups. Group A received low dose whole-lung irradiation combined with PF regimen. Group B receive PF regimen chemotherapy only. χ 2 test was used to the remission and survival rate of group A and group B were compared with statistical analysis. Results The CR and PR of group A were significant higher than that of group B(P< 0.05), and the PD rate of group A was lower than that of group B(P< 0.05). The NC rates between group A and group B had no statistical significance(P >0.05). Twelve- month survival rates between group A and group B had no statistical significance(P >0.05), while the 18, 24 and longer than 36 months survival rate of group A was significant higher than that of group B(P < 0.05). Conclusion Low dose whole-lung irradiation combined with PF regimen is currently an effective treatment modality for the treatment of lung metastases from NPC.
出处
《实用医学杂志》
CAS
2005年第16期1786-1787,共2页
The Journal of Practical Medicine
关键词
全肺照射
PF方案
鼻咽癌
肿瘤转移
疗效分析
Nasopharyngeal neoplasms Neoplasm metastsais Radiotherapy PF regimen
