摘要
目的 探讨川崎病（Kawasakidisease，KD）急性期并发冠状动脉损害（coronary artery lesions，CAL）的危险因素，以期减少KD发生CAL。方法 对2004-01／06我院收治的102例KD患儿的性别、年龄、临床表现、实验室检查、心脏彩超和治疗情况进行回顾性分析。结果 102例KD患儿中，作心脏超声检查发现CAL 32例（32．3％），其中冠状动脉瘤5例，冠状动脉扩张21例，管壁增厚6例。CAL与患儿的年龄、是否使用静脉丙种球蛋白（MG）和使用MG的时间密切相关，C-反应蛋白阳性、血沉增快可作为CAL的提示性指标。结论 一旦确诊KD，合理使用MG，可减少和预防CAL，有利于KD的康复。
Aim The goal of this study was to investigate the risk factors of coronary artery lesions （CAL） in Kawasaki disease（KD） in its acute phase, in order to reduce the incidence of CAL.Methods We performed a retrospective analysis in 102 patients with KD who stayed in our hospital from January to July 2004.The parameters studied were age, sex, andduration of the fever, erythroeyte sedimentation rate,hemoglobin, white blood cell count, and platelet count.Results Among those patients examined by echocardiography, 32 cases had CAL （5 with coronary aneurysm, 21 with coronary dilation, 6 with arterial wall thickening）. The findings suggested that it was close relationship between CAL and used intravenous immunoglobulin, and It was also very important when IVIG was used. The positive of C-reaction protein and erythrosedimentation increasing were perhaps correlated factors to cause CAL.Conclusion Intravenous immunoglobulin therapy is effective for reduction and prevent from the incidence of coronary artery lesions in Kawasaki disease, if IVIG is used reasonably in children with KD.
出处
《世界今日医学杂志》
2005年第3期147-148,共2页
World JOurnal of Medicine Today
