摘要
通过测定年龄在４２～４９岁之间患有更年期综合征表现为肾虚的妇女与正常妇女的骨密度值及血清促卵泡生成激素（ＦＳＨ）、促黄体生成激素（ＬＨ）、雌二醇（Ｅ＿２）值，以探讨近绝经期妇女骨矿含量与“肾”的关系。结果：肾虚组的桡尺骨密度及其均值明显低于正常组（Ｐ＜０．０１）；肾虚组的血清ＦＳＨ值较正常组显著增高（Ｐ＜０．０１）；肾虚组的血清Ｅ＿２值较正常组显著降低（Ｐ＜０．０１）。结果在明：①肾虚患者较非肾虚患者易患骨质疏松症，提示骨密度的微观检测可作为观察肾虚疗效的客观指标；②提示了近绝经期妇女骨矿含量随着雌激素水平的下降而减少，为补肾法防治近绝经期妇女骨质疏松症提供依据。
This paper explores the relationship between the bone mineral contents in menopausal womenand the kidney by determining the bone density values and serum FSH, LH, E_2 levels in womenwith the kidney-deficiency type menopausal syndromes and normal subjects aged from 42 to 49years.The results showed that the mean values of the radius and ulnar density in the kidney-de-ficiency women were significant lower than those in the normal women(P<0.01).Serum FSHlevels in kidney-deficiency women were significant higher than those in normal subjects group(P<0.01);While the serum E_2 levels in kidney-deficiency women were significant lower thanthose in normal subjects(P< 0.01).The results showed that :1)the kidney-deficiency patientsare much likely to have osteoporosis than non-deficiency patients,indicating that the determina-tions of bone density may be the objective indexes of the kidney-deficiency ; 2)bone mineralcontents in menopausal women decrease as their estrogen levels become lower, which supportsthat osteOporosis will be benefited by the kidney-strengthening therapy in Traditional ChineseMedicine.
关键词
肾虚
病理生理学
桡骨
尺骨
雌二醇
更年期
女性
KIDNEY ASTHENIA/physiopathol.RADIUS/anal.ULNA/anal.FSH/blood LH/blood ESTRADIOL/blood CLIMACTERIC FEMALE
