摘要
用超微结构及细胞化学方法,观察到腹腔注入秋水仙素后0.5h,大鼠肝细胞出现大量蝌蚪形、哑铃形、“C”形、环形和极不规则形溶酶体,同时观察了溶酶体的溶噬现象,认为溶酶体可能以出芽的方式进行自身降解.
After peritonel injection of colchicine, its effect on lysosomal autophagy of hepatic parenchymal cells was observed by transmission electron microscope and cytochemically. A great deal of irragular shaped lysosomes were shown at different periods of the lysosome wrapping mechanism ( LWM ) .The lysosomophagy which was named by Dr. Johan Thyberg could also be found in this study. We suggested that lysosome could be degraded by lysosome wrapping mechanism and lysosome budding.
出处
《第一军医大学学报》
CSCD
1989年第4期312-315,共4页
Journal of First Military Medical University
关键词
溶酶体
自噬
秋水仙素
超微结构
lysosome
autophagy
lysosomophagy
colchicine
transmission electron microscope
AcPase
