摘要
合成了１５个新的１－（取代异噁唑基）－１，２，４－三唑和１－（取代嘧啶基）－１，２，４－三唑化合物，经元素分析、ＩＲ、１ＨＮＭＲ和ＭＳ证实其结构。
?Oxo-α-(1,2,4-triazol-1-yl)ketene dithioacetals 1 reacted with hydroxylamine hydrochloride in the presence of barium hydrate in refluxing ethanol to give a mixture of isomeric 1-[5-alkylthioisoxazolyl)-1,2,4-triazoles 2 and 1-(3-alkylthioisoxazolyl)-1,2,4-triazoles 2'].Their mass spectral fragmentation was discussed respectively. On treatment with guanidine and thiourea in a refluxing sodium ethoxide, 1 afforded 1-(substitutedpyrimidinyl)-1,2, 4-triazoles 3 and 4. The preliminary biological tests show that isoxazolyltriazoles 2 and 2' have plant-regulatory activities.
出处
《高等学校化学学报》
CSCD
北大核心
1995年第11期1740-1743,共4页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
关键词
合成
取代异恶唑
三唑
取代嘧啶基
生物活性
Synthesis
1-(Substituted isoxazolyl)triazoles
Pyrimidinyl triazoles
Biological activity
