摘要
本文报告反复暂时性肝动脉阻断结合腹腔或肝动脉内化疗治疗２５例晚期不可切除肝恶性肿瘤的结果。２５例中１０例用肝动脉间歇阻断加腹腔５─氟尿嘧啶化疗，５例加经肝动脉导管灌注５─氟尿嘧啶化疗，１０例加经肝动脉大剂量顺铂“双路”化疗。治疗后５例肿瘤明显缩小，肿瘤直径小于原５０％。５例中３例为大剂量顺铂“双路”治疗，其中１例成功施行肿瘤序贯切除。全组治疗后平均存活时间为１１．３个月，最长存活５６个月，２例迄今仍存活。
Twenty five patients with unresectable liver cancer were treated by the method of repeated temporary blockade of the hepatic artery (RTBHA) with intrap eritoneal or intra -arterial chemotherapy.RTBHA with intraperitoneal 5-fluorouracil (5-Fu) infusion was carried out in 10 patients, intra-arterial infusion of 5-Fu in 5,and intra-arterial infusion of 'two-rout' high dose cisplatin (CDDP) in 10. Five of the 25 patients exhibited a marked tumor regression,the diameter of the tumor was 50% less than before, after the therapy.Three of the them were in high dose CDDP group in which one patient underwent a sequential tumor resection successfully.The mean survial of the patients was 11.3 months and two patients are still alive.The longest survival was 56 months.
出处
《肝胆外科杂志》
1995年第3期150-153,共4页
Journal of Hepatobiliary Surgery
