摘要
作者报告西京医院1976年8月至1988年10月收治的危重肺心病恿者458例,其中发生多脏器衰竭(MOF)者256例(55.9％),死亡82例,病死率为32.0％。MOF患者发生心肺以外1个脏器损害的病死率为13.0％,2个者为44.3％,3个或3个以上者为73.4％,其统计学差别非常显著(P<0.01)。作者对MOF的发病机理作了探讨。
Four hundred and fifty-eight patients with severe chronic cor pulmonale,or pulmonary heart disease, hospitalized from 1976 to 1988, are reviewed in this paper. Among them multiple organ failure ( MOF ) occurred in 256 cases with 82 cases died. The case fatality rate was 32.03%. And the case fatality rates in patients with one, two and three or more organ failures were 13.0%, 44.1% and 73.4% respectively. The differences between them are of statistical significance ( P<0 .01 ) . The pathogenetic mechanism for MOF is disscussed. We suggest that the infection may be the main factor of MOF in patients with chronic cor pulmonale, and that on the basis of infection, hypoxemia, CO2 retention and acid-base imbalance might contribute to the pathogenesis of multiple organ failure.
出处
《第四军医大学学报》
1989年第5期339-341,共3页
Journal of the Fourth Military Medical University
