摘要
采用脉冲辐解动态吸收光谱研究了咖啡酸对胸腺嘧啶、胸苷的阴离子自由基的快速修复过程，其机理是电子自嘧啶碱基及其衍生物的阴离子自由基向咖啡酸的快速转移。咖啡酸作为一种电荷转移保护剂，它具有比靶分子更高的单电子还原电位或电子亲合势。
Utilizing pulse radiolysis and kinetic spectrophotometric monitoring techniques, rapid electron transfer reaction from thymine and thymidine anion radicals to caffeic acid was observed respectively. Anion radicls of caffeic acid with absorption maximum at 360 nm haye been generated via foregoing electron transfer reaction with rate constant of 1 × 109mol-1L s-1. Accordingly the subsequent protonation of thymine anion radicals should be prevented by the electrophilic protector. These kinetic demonstrations have provided direct evidence of charge transfer protection mechanism.
出处
《辐射研究与辐射工艺学报》
CAS
CSCD
北大核心
1995年第3期140-145,共6页
Journal of Radiation Research and Radiation Processing
基金
国家自然科学基金
关键词
咖啡酸
胸腺嘧啶
胸苷
阴离子自由基
Caffeic acid, Thymine,Electron transfer, Charge transfer, Radiation protection
