摘要
作者观察了慢性缺氧对幼猪肺组织和肺小动脉壁钙调蛋白活性量的影响。缺氧动物的上述组织均在缺氧条件下取出。结果表明,①慢性间断性低压缺氧的幼猪在4000m模拟高原肺动脉增压反应明显。②缺氧动物肺组织钙调蛋白活性量较平原组显著增高。③在肺小动脉持续收缩时,取材测得肺小动脉壁钙调蛋白活性量与平原组相比无显著改变。说明缺氧性肺小动脉收缩不是通过影响平滑肌细胞内钙调蛋白活性量而实现的。
The effects of chronic hypoxia on calmodulin levels of lung tissue and intrapulmonary arteriolar wall in young pigs were studied .The specimens of hypoxic animals were taken under hypoxic condition from the hypoxic animals. It was observed that (1) the swine exposed to chronic intermittent hypobaric hypoxia showed significant pulmonary prcssor response at 4000m simulated high altitude , (2) the calmodulin level of lung was higher in hypoxic group than in sea level one , while that of intrapulmonary arteriolar wall exhibited no significant difference between hypoxic and control groups . The latter finding suggests that hypoxic pulmonary arteriolar constriction may not be associated with an obvious change of calmodulin level in vascular smooth muscle .
出处
《第三军医大学学报》
CAS
CSCD
北大核心
1989年第2期92-94,共3页
Journal of Third Military Medical University
关键词
缺氧症
钙调素
动脉
肺
高血压
Anoxia/ES
Hypertension, pulmonary
Calmodulin
Lung/AN
Arterioles , intrapulmonary/AN
