摘要
本实验通过对６６名不同胎龄新生儿，４０名患感染性疾病新生儿血清２０种游离氨基酸（ＦＡＡ）和前白蛋白（ＰＡ）的测定。实验表明：小于胎龄儿（ＳＧＡ）血中ＰＡ和部分ＦＡＡ较适于胎龄儿（ＡＧＡ）、大于胎龄儿（ＬＧＡ）显著降低；感染组新生儿血清中部分ＦＡＡ显著低于正常对照组，ＰＡ二组间无显著差异；ＳＧＡ组、感染组其氨基酸比率出现类似蛋白—能量营养不良ＦＡＡ图谱改变。结果提示：血ＰＡ和ＦＡＡ是评估新生儿蛋白营养不良的敏感指标。在感染情况下，血清ＰＡ将受到其它因素影响，应慎重选择。
In this study, the blood serum concentritions of 20 Free Amino Acid(FAA) and prealbumin(PA) were determined in 66 different gestational age of newborn and 40 newborn suffering from infectious disease. Our results indicated that small for gestational age(SGA) infants have significantly lower concentrations of PA and some FAA, compared with those of appropriate for gestational age(AGA) and large for gestational age(LGA) infants; Serum concentritions of some FAA in infectious newborn is lower than in normal newborn. No differences were observed between the infectious newborns and normal infants in PA. The values for Amino Acid ratios in SGA infants and infectious infants were similar to those found in protein-energy malnutrition. Our findings suggest blood serum PA and FAA might be used as sensitive markers to assess neonatal protein-energy malnutrition. Serum PA need to prudentially choosed in infectious disease because it will be affected by some other factors.
出处
《大连医科大学学报》
CAS
1995年第3期197-201,共5页
Journal of Dalian Medical University
